L. Erasmus
G. Weber
Corresponding Author: admin@greenbio.co.za
Pack size:
Application:
| List |
|---|
|
Bacillus coagulans |
|
Bacillus clausii |
|
Baciilus subtilis |
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Bifidobacterium bifidum |
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Bifidobacterium longum |
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Saccharomyces boulardii |
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Lactobacillus acidophilus |
|
Lactobacillus plantarum |
|
Lactobacillus rhamnosus |
|
Bromelain |
|
Gardenia jasminoides |
|
Eucommia ulmoides |
|
Rehmannia glutinosa |
| Ingredient | Inclusion |
|---|---|
|
Probiotic CFU 2 x 10⁹ /capsule |
8 mg |
|
Bromelain |
3 mg |
|
Gardenia jasminoides |
0,1 gram |
|
Eucommia ulmoides |
0,1 gram |
|
Rehmannia glutinosa |
0,1 gram |
|
Carrier |
89 mg |
Probiotics are live beneficial bacteria and/or yeasts, microbes, that occur naturally in the human body. A microbe is a probiotic when it can be isolated from the body; survive the intestinal environment after ingestion; proves to be beneficial to the body and can be safely consumed. Unfortunately, both good and bad bacteria are constantly found in the body. The purpose of good bacteria is to maintain a healthy balance in the body and eliminate bad bacteria which have entered the body due to diseases, inflammation, food products or a weakened immune system. Probiotic supplements are a helpful wayto add good bacteria and build a beneficial microbiome in the body.
Effectiveness of probiotics is well known: Probiotic bacteria stimulate or suppress immune responses; they improve gastrointestinal tract (GIT) immunity by supporting the cells of the GIT to prevent harmful bacteria entering the bloodstream and aid in controlling inflammation or infection. Since the GIT is the largest immunological organ in the body, containing 70-80% of immunoglobulin producing cells, the importance of probiotic bacteria is emphasized. In recognising their potential to modulate immune responses, it is also important to note these bacteria modify the microbial population of the GIT by promoting favourable GIT bacteria, hereby increasing the digestion and absorption of nutrients, production of antimicrobial substances and vitamins. They restore the beneficial intestinal microbiome after antibiotic treatments but also plays a role in enhancing the breakdown of medication.
Common probiotic bacteria include Bacillus, Bifidobacterium and Lactobacillus. The most common yeast is Saccharomyces boulardii. All of these probiotic bacteria have important health benefits through several mechanisms. Bacillus coagulans is lactic-acid producing bacteria and has antimicrobial, antidiarrheal and antioxidant activities. They produce different enzymes and metabolites which aid in these activities, hereby producing an overall shift in the GIT environment to support a complex intestinal microbiome.
Bifidobacterium bifidum have been studied for their effectiveness in preventing and treating a broad spectrum of GITdisorders. They have an antimicrobial, immune modulatory and anti-inflammatory effect.
Bifidobacterium longum has been shown to have immune stimulatory, antimicrobial and anti-inflammatory actions.
Lactobacillus bacteria (gram positive facultative anaerobic or microaerophilic rod-shaped) are lactic acid producing bacteria that normally occur in the human body and are commonly used for infectious GIT diseases or disorders, inflammation in the intestines and disturbed digestion or intestinal balance.
Lactobacillus plantarum has immune stimulative, antioxidant, anti-inflammatory protective and antimicrobial effects and it disturbs colonization of pathogenic bacteria. They are bacteria occurring naturally in our gut which altersthe intestinal microbiome favourably.
Lactobacillus rhamnosus has been shown to have an effect on the responsiveness of the immune system, on intestinal inflammation and to be protective against pathogenic bacteria. These bacteria have numerous benefits on the digestive system and overall health.
Saccharomyces boulardii is a probiotic yeast commonly used as a preventative and therapeutic treatment for digestion problems GIT infection and inflammation, and disorders dueto harmful organisms.
Bacillusclausii bacteria have antimicrobial and immune-modulatory activities.
Bacillus subtilis is common in nature and produces numerous antibiotics. Investigations identified B. subtilis strains as having immunostimulatory, antimicrobial, antiviral and anti-inflammatory effects.
Cautious use of a probiotic is important: When probiotics are taken by mouth, they are mostly safe for adults and children. Pregnant or breast-feeding women should always first consult a healthcare provider about the different strains of bacteria in probiotic products before usage. Subjects with a compromised immune system, short bowel syndrome, damaged heart valves and infants with a stomach or intestinal block should also consult a healthcare provider before taking probiotics freely. In some cases, taking probiotics for the first time might slightly upset the stomach and intestine, causing gas and bloating. Interaction between antibiotics and probiotic bacteria exists. To avoid a reduction in the effectiveness of probiotic bacteria, take probiotic products at least two hours before or after antibiotics. Similarly, medication used to treat fungal infection might also reduce the effectiveness of probiotic yeasts. Lastly, people that are allergic to yeasts can also be allergic to probiotic products containing Saccharomyces boulardii.
This enzyme extract refers to a cysteine protease mixture. ‘Protease’ is an enzyme that digests protein through catabolism, known as proteolysis. It is prepared from cooled pineapple juice through ultrafiltration, centrifugation and lyophilization, which results in the production of a powder. The composition of bromelain varies based on the source as well asthe method of preparation.
Bromelain has numerous therapeutic effects but is mostly used for its anti-inflammatory properties. Furthermore, it has beneficial effects on protein digestion, circulatory systems, mucus membranes and on the immune system.
According to research, bromelain prevents the biosynthesis of proinflammatory prostaglandin through indirect intervention. During any repeated stressful or traumatic situations accompanied by endogenous protease, the amount of proinflammatory prostaglandin raises. Bromelain has shown to be sensitive to those situations in a way similar to endogenous protease plasmin and works on fibrinogen. (Plasmin is a non-specific protease usually present in human serum, and it is responsible for degrading a variety of plasma proteins; its specific physiological role is to degrade fibrin clots.) Bromelain is absorbed into the bloodstream unchanged when consumed in significant amounts, increasing the fibrinolytic and proteolytic activity of blood.
Bromelain is distinct from other nonsteroidal anti-inflammatory medicines such as aspirin-like medications. It is beneficial to the prostaglandin synthetic pathway and does not induce unwanted side effects. It inhibits proinflammatory prostaglandin synthesis without influencing the synthesis of anti-inflammatory prostaglandins. In this way, it helps to restore the equilibrium of the two prostaglandins which is the healthier and more natural condition for living organisms.
Effectiveness of Bromelain: Bromelain is mostly used as an anti-inflammatory agent. Initial studies have found that bromelain has health benefits, anticancer effects, aids in wound healing and circulatory improvement and effectively treated some diseases and health conditions.
Cautious use of Bromelain: As with other supplemental products, talk with a health care provider before using the product. Bromelain might have mild side effects when taken in high doses. These include: diarrhoea, nausea, vomiting or abnormal bleeding. Some people may also experience allergic reactions and bromelain should not be used with other blood thinning products due to its antiplatelet effect.
Crude extract is from:
• The fruit of Gardenia jasminoides
• The bark of Eucommia ulmoides
• The root of Rehmannia glutinosa
All are common medicinal plants for traditional Chinese medicine and botanical health food purpose. These extracts contain a mixture of natural iridoid glycosides present in the plants and its physiological active compounds are highly bioavailable. These herbal extractions are used as a liver booster to help and maintain a healthy liver. The extraction process is enzymatic and no solvents are used.
Iridoids are a group of organic chemical compounds, a type of monoterpenoid, usually as glycosides with a glucose moiety attached to in the pyrene ring and is found in many plant families. These compounds have been regarded as defence chemicals produced by the plants. The most common iridoids are: gardenoside, geniposide, genipin, geniposidic acid, a ucubin, catalpol, loganin, patrinoside.
Iridoids have a hepaprotective effect attributed to their anti-oxidant, anti-inflammatory activity. An indirect action is to stimulate the antioxidant defence system and their direct action is to remove reactive oxygen species. Some of these compounds also have a choleretic action which aids in bile secretion.
The effectiveness of these compounds is well studied: It can serve as treatment for toxicosis, indigestion, liver failure, ketosis, lack of appetite, dyspepsia with meteorism and as an adjuvant in the treatment of intestinal parasites. It aids in liver functions, reduce excessive fat accumulations in the liver and increase hepatic capacity for the oxidation of fatty acids. It stimulates bile production in the liver and promotes the secretions of bile from the liver and can help to treat fatty liver and digestive disorders. Reproductive systems can be beneficially affected with treatment of these extracts due to an increase in cholesterol availabilityfor the synthesis of hormones, general liver function and enhanced energy metabolism.
Cautious use of these extracts is important: There is not sufficient knowledge about the use of Gardenia jasminoides during pregnancy and breast-feeding. Consult a healthcare professional before using this product. It may have a laxative effect and, as such, caution should be exercised when using it in combination with other stimulative laxatives. During one study, possible concerns were documented with the use of Eucommia ulmoides. It included moderate headache and a cold, light dizziness and edema. This product might contain components to which some people express hypersensitivity and might also be contraindicated in people with estrogen-dependent cancers. The use of Rehmannia glutinosa is safe when taken by mouth although there is not much information about its effect if taken for longer than 8 weeks. Consult a healthcare professional before using this product due to insufficient knowledge about its use during pregnancy or breast-feeding. R. glutinosa might affect blood glucose levels and can possibly interfere with blood sugar during and after a surgery. It is recommended to rather stop using it 2 weeks before surgery at least. Also, be aware that the over use of products containing R. glutinosa might cause diarrhoea, loss of appetite, fatigue and palpitations.
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