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TerraVIT Plus Multi-vitamin Product Information

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• Author

L. Erasmus

G. Weber

Corresponding Author: admin@greenbio.co.za

• Ingredients - Nutritional Information - Each Capsule Contains

Presentation: 30 Capsules, 60 Capsules & 1000 Capsules (Pharmacies only – not for sale to the public).

Storage: Store below 25 ⁰C in a cool dry area. Protect from light and moisture.

Dosage And Direction For Use: Adults and children over 12 years: Take 2 Capsule daily.

Vitamins

Ingredient Serving
Ascorbic Acid (Vitamin C)
20 mg
Biotin
0,3 mg
Cyanocobalamin (Vitamin B12)
0,7 µg
Folic Acid (Vitamin B9)
80 µg
Niacin (Vitamin B3)
8 mg
Pantothenic Acid (Vitamin B5)
2 mg
Pyridoxine (Vitamin B6)
0,8 mg
Riboflavin (Vitamin B2)
0,7 mg
Thaimine (Vitamin B1)
0,5 mg
Vitamin A
450 µg
Vitamin D3
8 µg
Vitamin E
1,5 mg
Vitamin K1
10 µg

Minerals

Nutrient Serving Size
Chromium
15 µg
Copper
0,44 mg
Iron
10 mg
Magnesium
130 mg
Manganese
1,5 mg
Molybdenum
22 µg
Selenium
30 µg
Zinc
5 mg
Bioflavonoid Complex
100 mg
9-Strain Probiotic Blend
8 mg

DRV = Daily Reference Value (Adults and Children older than 10 years).
No DRV Established.
Sugar Free, contains no lactose or caffeine.
Pharmacological Classifications: Complimentary Medicine Category- Combination Complimentary Medicine “Vitamin Mineral Supplement”

• Information

Indications

TERRAVIT PLUSMULTIMINERAL VITAMIN SUPPLEMENT combines essential Iron Ferrochel Amino Acid chelated Mineral, Zinc Glycinate Amino Acid Chelated Mineral, Magnesium Glycinate Amino Acid Chelated Mineral, Manganese Glycinate Amino Acid Chelated Mineral, Copper Glycinate Amino Acid, Chelated Mineral Selenium Amino Acid Chelated Mineral Complex, Molybdenum Amino Acid Chelated Mineral Complex, Vitamin A Palmitate Vitamin B1, Vitamin B2, Vitamin B3, Vitamin B5, Vitamin B6, Vitamin B9, Vitamin B12, Vitamin C, Vitamin E (Acetate Tocopherol) Vitamin D3 and Bioflavonoid Complex which is necessary for the maintenance of good health and vitality.


TERRAVIT PLUS MULTIMINERAL VITAMIN SUPPLEMENT – Can be taken by Adults and Children over 10 years of age,
Elderly age group, Convalescent and Post Operative patients, Students and Sports Individuals.

TerraVit Plus Multi-mineral Vitamin Supplement

Contains Iron Ferrochel Amino Acid chelated Mineral, Zinc Glycinate Amino Acid Chelated Mineral, Magnesium Glycinate Amino Acid Chelated Mineral, Manganese Glycinate Amino Acid Chelated Mineral, Copper Glycinate Amino Acid Chelated Mineral Selenium Amino Acid Chelated Mineral Complex, Molybdenum Amino Acid Chelated

Mineral Complex, Vitamin A Palmitate Vitamin B1, Vitamin B2, Vitamin B3, Vitamin B5, Vitamin B6, Vitamin B9, Vitamin B12, Vitamin C, Vitamin E (Acetate Tocopherol) Vitamin D3 and Bioflavonoid Complex which is necessary for the maintenance of good health and vitality.

Iron Ferrochel Bis-Glycinate Acid Chelated Mineral is well Absorbed, Regulated and Utilized by the body without any interference from other Mineral Compounds or the diet. The composition in the TerraVIT PLUS Multimineral Vitamin Supplement advances improvement in health and ameliorating iron deficiency, iron deficiency anaemia, causal through several physiological and biological conditions without masking and or disguising Folate deficiency and Vitamin B12 deficiency. In addition, the combination of ingredients assists with the healthy formation of red blood cells.

Iron is important for the formation of haemoglobin which carries oxygen to all body cells. The red corpuscles of the blood need iron for their formation. Growing children and menstruating woman and pregnant woman require more iron than other population groups. Iron aids in energy production and cell diffusion whilst helping the immune and

central nervous system function optimally. Iron is of great importance in human nutrition. The adult human body contains between 3 – 4 g of iron of which 60 – 70% is present in the blood as circulating iron and the rest 1 – 1.5 g as storage iron. Each gram of haemoglobin contains approximately 3.34 mg of iron.

Zinc Glycinate Amino Acid Chelated Mineral: Is well Absorbed, Regulated and Utilized by the body without any interference from other Mineral Compounds or the diet. Zinc plays an important role in Glucose Metabolism, Cellular Reproduction and Repair and is beneficial for Wound Healing, Vision and Neurotransmission. Zinc assists the immune function and defence against free radical damage and is also known to assist with retarding inflammation, infection and stress whilst maintaining hormone balance, decreasing oxidative stress and incidence of infection. Zinc supports Prostate function in males.

Zinc is an essential trace element necessary for humans, plants animals and microorganisms. Zinc is found in nearly 100 specific enzymes serves as structural ions in transcription factors and is stored and transferred in metallothioneins. It is typically the second most abundant transition metal in organisms after iron and it is the only metal which appears in all enzyme classes.

Magnesium Glycinate Amino Acid Chelated Mineral: Magnesium Glycinate is well Absorbed, Regulated and Utilized by the body without any interference from other Mineral Compounds or the diet. The inclusion of Magnesium Glycinate is to assist the body in optimizing its enzymatic processing, without any interference from any source of Calcium as is the case when inorganic Calcium is used in other Vitamin – Mineral blends. Unlike other Magnesium Oxides or Inorganic Magnesium Minerals the Amino Acid Mineral Magnesium is absorbed mainly in the Jejunum and not the Duodenum thus it is not subjected to the digestive acids of the stomach.

Magnesium is the 11th most abundant element by mass in the human body: its ions are essential to all living cells where they play a major role in manipulating important Biological Polyphosphate compounds like ATP, DNA and RNA. Hundreds of enzymes thus require Magnesium ions to function. Magnesium is a vital component of a healthy

human diet. Human Magnesium deficiency is relatively common, with only 32% of the population of the United States meeting RDA/RDI intake levels. Low levels of Magnesium in the body have been associated with the development of a number of human illnesses such as Asthma, Diabetes and Osteoporosis. Magnesium regulates the absorption of Calcium and is involved in the structural integrity of Bones and Teeth. If it is deficient in the bones, the bones may be dense but have poor Trabecular integrity and thus be brittle. Magnesium regulates the contractility of the heart muscle. It is concentrated 18 X greater in the heart muscle than in the blood stream. A decreased Magnesium level in the heart muscle may predispose an individual to Coronary Spasms. Magnesium has a relaxing effect on smooth muscle. It may be helpful in relaxing the smooth muscle of Bronchioles (assisting Asthma reduction) and the arterioles (lowering Blood Pressure).

Manganese Glycinate Amino Acid Chelated Mineral: The Human body contains approximately 10/mg of manganese, which is stored mainly in the liver and kidneys. In the human brain Manganese is bound to manganese metalloproteins most notably glutamine synthetase in astrocytes. Manganese (II) ions function as cofactors for a

number of enzymes in higher organisms, where they are essential in detoxification of superoxide free radicals. The element is a required trace mineral for all known living organisms and assists the body to utilize several key nutrients such as biotin, thiamine, ascorbic acid and choline, keeps bones strong and healthy, assists the body’ to synthesize fatty acids and cholesterol and maintain normal blood sugar levels. Manganese also promotes optimal thyroid gland function, maintain the health of nerves and protect cells from free radical damage.

 

Copper Glycinate Amino Acid Chelated Mineral: The adult human body contains between 80 – 150/mg of copper. The liver is the major location of stored copper, containing about 10% of the total-body content. Copper is rapidly absorbed from the stomach and small intestine. Zinc, Molybdenum and Vitamin C are strong antagonists of copper. The role of copper in maintaining cardiovascular health is well established. Copper is essential both for its role in Lysyl Oxidase, essential for the strength and integrity of the heart and blood vessels. With such a central role in cardiovascular health as well as both its role in antioxidant enzymes, Copper and Zinc Superoxide Dismutase and Ceruloplasmin. Copper deficiency may produce many of the abnormalities present in cardiovascular disease. Copper plays a vital role in the biosynthesis of bone and connective tissues and their maintenance.

 

Molybdenum Amino Acid Chelated Mineral: The human body contains approximately 0.07 mg of molybdenum per kilogram body weight. It occurs in higher concentrations in the liver and kidneys and in lower concentrations in the vertebrae. Molybdenum is also present within human tooth enamel and may help prevent its decay. The average daily intake of molybdenum varies between 0.12 and 0.24 mg, but it depends on the molybdenum content of the food source. Acute toxicity has not been seen in humans and the toxicity depends strongly on the chemical state. High levels of molybdenum can interfere with the body’s uptake of copper, producing copper deficiency. Molybdenum prevents plasma proteins from binding to copper and it also increases the amount of copper that is excreted in urine.

 

Selenium Amino Acid Chelated Mineral Complex: Is most well-established role as a component within the active site of the antioxidant enzyme, Glutathione Peroxidase. Glutathione Peroxidase helps prevent the generation of free radicals and decreases the risk of oxidative tissues, including the Kidney and its vascular components. Low Selenium intake and status if of concern during chronic renal failure, when dietary protein restrictions are necessary, because dietary selenium is primarily associated with protein. Depressed selenium status occurs frequently in renal patients and should be of concern because of the possible exacerbation of comorbid conditions. Oral selenium supplements have proven to be effective in improving the selenium status and immune function of renal patients while simultaneously decreasing the products of oxidative stress.

 

Selenium is an essential element involved primarily in enzymes that are antioxidants, three selenium containing enzymes are antioxidant peroxidase and a fourth selenium-containing enzyme is involved in thyroid hormone production. The prostate contains a selenium containing protein and semen contains relatively large amounts of

selenium. In combination with Vitamin E, selenium aids the production of antibodies and helps maintain a healthy heart, it also aids in the function of the pancreas, provides elasticity to tissues and helps cells defend themselves against damage from oxidation.

 

Vitamin A Palmitate: The most important function of Vitamin A is to maintain the functionality of the rod’s cells in the eyes. These cells are responsible for night vision. Vitamin A is also important for skin texture. Deficiency of Vitamin A causes a condition called Xeropthalmia or night blindness wherein the individual cannot see clearly in the

Dark.

 

Vitamin B Group: The B Vitamin Complex plays many important roles in the body. Vitamin B Complex improves the body’s resistance to stress. Aids in digestion, promotes good muscle tone, healthy skin, reduces muscle spasms, leg cramps, hand numbness and assists in regulating blood pressure. The B Vitamin Complex is involved in an

extremely large and important group of metabolic functions in the human body, such as energy production, Interco versions of one substance to another, detoxification, nerve transmission, blood formation, synthesis of proteins and fats, the production of steroid hormones, the maintenance of blood sugar levels, the maintenance of appetite, the toning of muscles etc. It is needed to counter the effects of stress, bolster the glands (especially the adrenal glands which become easily exhausted when subjected to stress) B Vitamin Complex is beneficial for healthy hair, skin and nails, red blood cells, antibody production, prevention of muscle cramps and spasms and elasticity of body tissue.

Vitamin B1 – Thiamine: Is absolutely essential to several bodily functions. Thiamine is a coenzyme for decarboxylation of pyruvate and the oxidation of alpha keto-glutamic acid. Thiamine aids the nervous system and is essential for the functioning of important enzymes. These enzymes have vital roles in the processes that make energy available in the body. Thiamine is essential for transmission of certain types of nerve signal between the brain and the spinal cord. Depression, poor memory, muscle weakness and stiffness, nerve tingling, burning sensation and numbness, tiredness, headache, loss of appetite and nausea are some of the symptoms and signs of Thiamine deficiency.

 

Vitamin B2 – Riboflavin: Is a water-soluble vitamin that supports energy metabolism and biosynthesis of a number of compounds through its coenzyme forms, flavin, adenine dinucleotide (FAD) and flavin adenine mononucleotide (FMN) Riboflavin is also required for activation and support of activity of Vitamin B6, B9, B3 and Vitamin K. Riboflavin is vital for normal reproduction, growth, repair and development of body tissues, including the skin, hair, nails, connective tissue and immune system. Severe Riboflavin deficiency is rare and often occurs with other B Vitamin deficiencies.

 

Vitamin B3 – Nicotinamide: Is a form of Vitamin B3 that may preserve and improve beta cell function. Nicotinamide is essential for growth and conversion of foods to energy. It has been used in diabetes treatment and prevention. Nicotinamide, via its major metabolite NAD++ (Nicotinamide adenine dinucleotide) is involved in a wide range of biological processes, including the production of energy, the synthesis of fatty acids, cholesterol and steroids, signal transduction and the and the maintenance of the integrity of the genome. It is also required for cell respiration and normal secretion of bile and stomach fluids and plays an important role in ridding the body of toxic and harmful chemicals.

 

Vitamin B5 – Pantothenic Acid: Is alternatively known as Vitamin B5. Pantothenic Acid is involved in a number of biological reactions, including the production of energy, the catabolism of fatty acids and amino acids, the synthesis of fatty acids, phospholipids, sphingolipids, cholesterol and steroid hormones and the synthesis of heme and the neurotransmitter acetylcholine. Pantothenic Acid is integral to many of the activities of enzymes in the human body. It is necessary for the manufacture of energy from both sugars and fats in the system as well as the utilization of other vitamins.

 

Vitamin B6 – Pyridoxine: Is an essential Vitamin to aid in the formation of healthy red blood cells and supports more vital bodily functions than any other Vitamin. Water soluble Vitamin, Vitamin B6 is needed to release energy from the food consumed. Vitamin B6 or Pyridoxine is a coenzyme for enzymes involved in amino acid metabolism.

Demination, transmination and decarboxylation of amino acids are required for synthesis, oxidation, and degradation of critical amino acid derived molecules that participate in haematological, neurological, humoral and inflammatory processes.

 

Vitamin B9 – Folic Acid: Folic Acid works closely with Vitamins B6 and B12 as well as the nutrients Betaine and S-adenosylmethionine (SAMe) to control blood levels of the amino acid homocysteine. Vitamin B9 has a direct effect on lessening depression. It helps regulate sleep and appetite, is crucial for proper brain function and plays an important role in mental and emotional health. Folic Acid is the synthetic form of this Vitamin that is found in supplements. Folic Acid deficiency is the most common B vitamin deficiency.

 

Vitamin B12 – Cyanacobalamine: Is one of eight water soluble B Vitamins. Cyanacobalamine is considered the most potent vitamin and is one of the last true vitamins that has been classified. Vitamin B12 is an especially important vitamin for maintaining healthy nerve cells and it aids in the production of DNA and RNA, the body’s genetic material. Vitamin B12 also works closely together with vitamin B9 to regulate the formation of red blood cells and to assist iron to function better in the body. Cyanacobalamine deficiency can cause a range of symptoms including fatigue, shortness of breath, diarrhoea, nervousness, numbness or tingling sensation in the fingers and toes.

Vitamin C – Ascorbic Acid: Vitamin C has multiple functions as either coenzyme or cofactor. Vitamin C is responsible for helping to build and maintain the tissues and strengthening the immune system, is essential for the oxidation of phenylalanine and tyrosine, the conversion of folacin to tetrahydrofolic acid. In addition, vitamin C may

modulate prostaglandin synthesis to favour the production of eicosanoids with antithrombotic and vasodilatory activity. Vitamin C is required for synthesis of dopamine, noradrenaline and adrenaline in the nervous system or in the adrenal glands and is also needed to synthesise carnitine, important in the transfer of energy to the cell mitochondria. Ascorbic Acid is required for collagen synthesis and has a structural role in bone, cartilage and teeth.

 

Vitamin E – Tocopherol: The most important function of vitamin E is to maintain the integrity of the body’s intracellular membrane by protecting its physical stability and providing a defence line against tissue damage caused by oxidation. Vitamin E is protective because it helps reduce oxidation of lipid membranes and the unsaturated fatty acids and prevents the breakdown of other nutrients by oxygen. Vitamin E is an antioxidant that prevents free radical damage in biological membranes. Free radicals can cause cell damage that may contribute to the development of cardiovascular disease and cancer. Vitamin E has an effect on several enzyme activities and membrane properties. It is involved in the regulation of vascular smooth muscle cell proliferation and protein kinase C activity. Vitamin E as an antioxidant helps to stabilize cell membranes and protect the tissue of the skin, eyes, liver, breast and testes, which are more sensitive to oxidation. When applied to the skin, vitamin E containing creams and oils are believed to promote healing, protecting cells from free radical damage and reducing itchiness. The protective nutritional antioxidant function of vitamin E is also performed and enhanced by other antioxidants, such as vitamin C and the mineral Selenium.

 

Vitamin D: The major biological function of vitamin D is to maintain normal blood levels of calcium and phosphorus. Vitamin D aids in the absorption of calcium, helping to form and maintain strong bones. Without vitamin D, bones can become thin, brittle and soft. Vitamin D prevents rickets in children and osteomalacia in adults. Exposure to sunlight is an important source of vitamin D. Ultraviolet (UV) rays from sunlight trigger vitamin D

synthesis in the skin.

 

Bioflavonoid Complex (45% HPLC) is derived from a large and diverse family of citrus Bioflavonoids which used to be referred to collectively as Vitamin P (The P standing for “Capillary permeability factor”) These are not strictly vitamins but are a group of special health-giving nutrients which cannot be made by the body and have to be obtained through the diet. Citrus Bioflavonoids have many health-giving properties including promoting healthy circulation and helping to maintain the thin walls and structure of blood capillaries. Bioflavonoids have antibacterial properties, assist in bile production and assist in the control of cholesterol levels. Sports injuries are widely treated by taking a Bioflavonoid Complex supplement to assist in the relief of pain and with the healing of bruises and excessive bleeding. Other benefits of Bioflavonoid Complexes is assistance in circulation, regulation of cholesterol and the prevention of cataracts, hemorrhoids, leg ulcers and nosebleeds by strengthening the walls of blood vessels. There are no established toxicity levels for Citrus derived Bioflavonoids, but extreme doses may cause diarrhea.

Contraindications

Iron Ferrochel Amino Acid

Hypersensitivity and anemias without proper work up i.e. documentation of iron deficiency. Hypersensitivity reactions can be very dramatic if iron is administered intravenously.

Not to be included in the treatment of Pernicious anemia (a decrease in Red Blood Cells that occurs when the body cannot properly absorb Vitamin B12 from the gastrointestinal tract.)

Not to be taken if “Bleeding internally”.

Not to be taken if Megaloblastic Anemia diagnosed through Alcohol abuse, certain inherited disorders, drugs that affect DNA such as Chemotherapy drugs, Leukemia, Myelodysplastic syndrome and Myelofibrosis.

Zinc Glycinate Amino Acid If you are allergic to zinc do not take this supplement due to increased risk of developing a severe and potentially life-threatening allergic reaction.

Adult woman who are pregnant or breastfeeding should limit their intake of zinc to 15/mg per day to avoid pregnancy or infant development complications.

People living with HIV or AIDS should avoid using zinc supplements, as treatment with this dietary mineral may reduce their life span.

Copper Glycinate Amino Acid – If you allergic to zinc do not take this supplement.

Magnesium Glycinate Amino Acid – The most common symptom of excess oral magnesium is diarrhea.

Manganese Glycinate Amino Acid– There are no recorded contraindications for Manganese.

Selenium Amino Acid is contraindicated in those who are hypersensitive to any component of a Selenium containing preparation

Molybdenum Amino Acid – There is no recorded contraindications for Molybdenum

Vitamin A Palmitate – Consult your Physician if Pregnant or Breast feeding

Vitamin B1 – Thiamine – None Known

Vitamin B2 – Riboflavin – None indicted other than high doses above 10/mg a day which could affect cataracts of the eye

Vitamin B3 – Nicotinamide – May cause flushing in high doses

Vitamin B5 – Pantothenic Acid – Is not known to cause side effects, except in excessively large doses

Vitamin B6 – Pyridoxine – is contraindicated in patients with a history of hypersensitivity to it

Vitamin B9 – Folic Acid is contraindicated in patients who have shown previous intolerance to the Vitamin

Vitamin B12 – Cyanacobalamine is contraindicated to sensitivity of Cobalt and or Vitamin B12

Vitamin C Contraindicated in those persons who have shown hypersensitivity to any component of this preparation

Vitamin D – Individuals with high calcium blood levels and Parathyroid disease should consult a physician prior to taking vitamin D

Vitamin E – Contraindications have not yet been identified

Bioflavonoids, including Hesperidin, tend to reduce blood platelet stickiness and therefore individuals taking blood thinners should consult with their physician prior to commencing supplementation

Pregnant and lactating woman should notify their doctor prior to taking Hesperidin supplements.

Warnings

Iron Ferrochel Amino Acid– Do not exceed the recommended daily dosage of Iron Ferrochel Bis-Glycinate Amino Acid Chelated Mineral.

Zinc Glycinate Amino Acid – If you are pregnant, or breast feeding consult your physician

Copper Glycinate Amino Acid – If you are pregnant, or breast feeding consult your physician

Magnesium Glycinate Amino Acid – Could cause diarrhea/ vomiting in high doses

Manganese Glycinate Amino Acid – If you are pregnant, or breast feeding consult your physician

Molybdenum Amino Acid – If you are pregnant, or breast feeding consult your physician

Selenium Amino Acid – If you are pregnant, or breast feeding consult your physician

Vitamin A Palmitate – If you are pregnant or breast feeding consult your physician

Vitamin B1 – Anaphylaxis as an adverse systemic reaction to thiamine

Vitamin B2 – May have synergistic effect with antimalarial prescription drugs

Vitamin B3 – Niacin should be avoided in patients with hepatic dysfunction

Vitamin B5 – If you are pregnant consult your physician

Vitamin B6 – If you are pregnant consult your physician

Vitamin B9 – May hide symptoms of vitamin B12 deficiency

Vitamin B12 – If you are pregnant consult your physician

Vitamin C: Diabetics, patients prone to recurrent renal calculi, those undergoing stool occult blood tests, and those on sodium-restricted diets or anticoagulant therapy should not take excessive doses of vitamin C over an extended period of time

Vitamin D – No warnings indicated

Vitamin E – Tocopherol Acetate – Any individual with diabetes, high blood pressure, an overactive thyroid or rheumatic heart disease should consult with their physician prior taking vitamin E the citrus Bioflavonoid tangeretin neutralizes the beneficial tumor-sppressing effect of tamoxifen. Bioflavonoids could have Inhibition of tamoxifen’s therapeutic benefit by tangeretin in mammary cancer.

Interactions

Iron Ferrochel Bis-Glycinate Amino Acid Chelated Mineral – lack of interactions with other minerals and vitamins, tannins, phenols and phytates.

Zinc Glycinate Amino Acid Chelated Mineral – Zinc supplements may interact with cisplatin, penicillamine, and quinolone and tetracycline antibiotics. In addition, captopril, cholestyramine, corticosteroids, deferoxamine, disulfiram, EDTA and EDTA derivatives, estrogens, ethambutol, H2-blockers, phenytoin, proton pump inhibitors, thiazide diuretics, and valproic acid may increase the need for zinc.

Copper Glycinate Amino Acid Chelated Mineral – Studies indicate that taking certain antipsychotic, nifedipine or birth control pills may alter copper levels in the body although clinical significance is unknown.

Magnesium Glycinate Amino Acid Chelated Mineral – A particularly long list of prescription medications have been shown to reduce the body’s supply of magnesium. Several types of diuretics used to lower blood pressure, including thiazide diuretics like Diuril ™ or Enduron, ™ and loop diuretics like furosemide, have been shown to

compromise magnesium status. Antibiotics can also lower magnesium availability. Included on the antibiotic list are neomycin, tetracycline, erythromycin, sulfamethoxazole, and sulfonamides. Other medications that reduce the body’s supply of magnesium include the anticoagulant drug warfarin; corticosteroids; oral contraceptives (birth control pills); and the immunosuppressant drug cyclosporine.

Manganese Glycinate Amino Acid Chelated Mineral – Manganese might decrease how much antibiotic the body absorbs. Taking Manganese along with some antibiotics might decrease the effectiveness of some antibiotics. To avoid this interaction, take Manganese supplements at least one hour after antibiotics.

Molybdenum Amino Acid Chelated Mineral – Molybdenum may affect Biliary obstruction or renal dysfunction.

Selenium Amino Acid Chelated Mineral – When certain medications, such as aspirin or statin cholesterol medications, are taken with Selenium, drug interactions may occur.

Vitamin A Palmitate – Anticoagulants (blood thinners) — Long-term use of vitamin A or taking high doses may increase the risk of bleeding for those taking blood-thinning medications, particularly warfarin (Coumadin). Talk to your physician before taking vitamin A. Cholesterol-lowering medications (bile acid sequestrants) — The medications cholestyramine (Questram) and colestipol (Colestid) may reduce the body’s ability to absorb vitamin A and lead to lower levels in the body. A water-soluble form of Vitamin A may help. Another class of cholesterol- lowering medications called statins may actually increase Vitamin A levels in the blood. Doxorubicin — Test tube studies suggest that vitamin A may enhance the action of doxorubicin, a medication used to treat cancer. More research is needed, however, to know whether this has any practical application. If you are undergoing treatment for cancer, talk to your oncologist before taking Vitamin A or any supplement. Neomycin (Mycifradin) — This antibiotic may reduce the body’s ability to absorb Vitamin A, especially when taken in large doses.

Vitamin B1 – Thiamine – Digoxin Diuretics Scopolamine containing Medications Tetracycline Tricyclic Antidepressants.

Vitamin B2 – Riboflavin – Antimalarial Medications, Antipsychotic Medications, Birth Control Medications, Doxorubicin Phenytoin-containing Medications, Selegiline, Tetracycline, and Tricyclic Antidepressants.

Vitamin B3 – Nicotinamide Alpha-blockers, Aspirin, Cholesterol-lowering, Medications Glipizide, GlyburideInsulin Preparations, Metformin-containing Medications Smoking-cessation Products Tetracycline.

Vitamin B5 – Pantothenic Acid – Don’t take Pantothenic acid if you have haemophilia. It might extend the time it takes for bleeding to stop. It is not known if this product interacts with any medicines. There are no known interactions with foods.

Vitamin B6 – Pyridoxine Antipsychotic Medications, Birth Control Medications, Hydralazine Levodopa Phenytoin-containing Medications, Tetracycline Theophylline-containing Medications, Tricyclic Antidepressants.

Vitamin B9 -Folic Acid should not be taken at the same time as the antibiotic “Tetracycline” because it interferes with the absorption and effectiveness of this medication. Antacids, H2 Blockers, Proton pump inhibitors, Bile Acid sequestrants, Carbamazepine, Nonsteroidal anti-inflammatory drugs (NSAIDSs), Sulfasalazine, and Triamterene will lower levels of absorption of Folic Acid.

Vitamin B12 – Cyanacobalamine – can potentially interact with different medication which may lead to drug interactions that include “Tetracycline” antibiotics H2 Blockers, Tagamet, Zantac, Rennies, Proton pump inhibitors, Chemotherapy Drugs and anti-inflammatory drugs (NSAIDSs).

Vitamin C: Limited evidence suggests that ascorbic acid may influence the intensity and duration of action of bishhydroxycoumarin.

Vitamin D – Agents which interfere with lipid absorption, such as cholestyramine, Orlistat, mineral oil (liquid paraffin) inhibits vitamin D3 absorption.

Vitamin E: Orlistat may reduce vitamin E absorption. Vitamin E may increase the anticoagulant effect of warfarin and may decrease the benefits of atrovastatin.

Bioflavonoids – there are no known drug interactions.

Pregnancy & Lactation

Iron Ferrochel Amino Acid – Any individual who has an increased iron requirement, pregnant and lactating woman should take Iron supplements under supervision from their physician.

Zinc Glycinate Amino Acid – The daily requirement for zinc during pregnancy is 15 milligrams.

Copper Glycinate Amino Acid – Pregnant women: 1 milligram (mg) per day Breastfeeding women: about 1.3 mg.

Magnesium Glycinate Amino Acid – For pregnant and lactating woman approximately 300 mg per day is considered safe.

Manganese Glycinate Amino Acid – If you are pregnant, or breast feeding consult your physician.

Molybdenum Amino Acid – If you are pregnant, or breast feeding consult your physician.

Interactions

Selenium Amino Acid – If you are pregnant, or breast feeding consult your physician

Vitamin A Palmitate – If you are pregnant or breast feeding consult your physician

Vitamin B1 – For pregnant woman 1.3 – 1.5 milligrams daily

Vitamin B2 – For pregnant woman 1.6 – 1.8 milligrams daily

Vitamin B3 – Niacin for pregnant and lactating woman could be taken up to 18 milligrams daily

Vitamin B5 – 4- 7 milligram is required during pregnancy daily

Vitamin B6 – 1.9 milligrams of pyridoxine is adequate during pregnancy and lactation daily

Vitamin B9 – Folic Acid during pregnancy is 400 – 800 mcg/daily. Folic Acid is actively excreted into human milk. No adverse effects in nursing infants have been associated with the use of Folic Acid during lactation. Folic Acid is considered compatible with breast feeding by the American Academy of Paediatrics. The recommended maternal

daily allowance of Folic Acid during lactation is 500/mcg.

Vitamin B12 – is actively transported to the foetus. This process is responsible for the progressive decline of maternal levels that occurs during pregnancy

Vitamin C: 85 milligrams vitamin C daily intake is adequate during pregnancy and lactation

Vitamin D – Not indicated for pregnant and breast-feeding woman

Vitamin E – Tocopherol Acetate – High-dose Vitamin E supplementation should be used with caution a maximum safe dose for pregnant woman or lactating mothers is 15 I.U. daily

Bioflavonoids during pregnancy and or during lactation it is recommended to consult your physician before commencing supplementation

Side Effects And Special Precautions:

Iron Ferrochel, possible gastrointestinal irritation.

Zinc Glycinate Amino Acid Chelated Mineral – To avoid side effects do not exceed the daily dosage

Copper Glycinate Amino Acid Chelated Mineral – To avoid side effects do not exceed the daily dosage

Magnesium Glycinate Amino Acid Chelated Mineral – To avoid side effects do not exceed the daily dosage

Manganese Glycinate Amino Acid Chelated Mineral – To avoid side effects do not exceed the daily dosage

Molybdenum Amino Acid Chelated Mineral – To avoid side effects do not exceed the daily dosage

Selenium Amino Acid Chelated Mineral – To avoid side effects do not exceed the daily dosage

Vitamin A Palmitate – No side effects at prescribed dosage recorded. Precaution – Pregnant and breast-feeding woman consult a physician

Vitamin B1 – Thiamine – No side effects or special precautions at prescribed dosage

Vitamin B2 – Riboflavin – No side effects or special precautions at prescribed dosage

Vitamin B3 – Nicotinamide – No side effects or special precautions at prescribed dosage

Vitamin B5 – Pantothenic Acid – No side effects or special precautions at prescribed dosage

Vitamin B6 – Pyridoxine – No side effects or special precautions at prescribed dosage

Vitamin B9 – Folic Acid has few side effects even when taken in high dosages. Although the Folic Acid itself is not a problem, supplemental Folic Acid can mask symptoms of pernicious anaemia. Very high dosages, above 15,000 mcg can cause stomach problems, sleep disturbances, skin reactions and seizures.

Vitamin B12 is likely to be safe for most people when taken orally. In some individuals Vitamin B12 might cause diarrhoea, blood clots, itching, serious allergic reactions and other side effects. Leber’s Disease, a hereditary eye disease, do NOT take Vitamin B12 if you have this disease or if you have an allergy or sensitivity to cobalt or Cobalamin.

Bioflavonoid Complex should not be taken by those with increased iron absorption, diabetes, folk acid deficiency, serious kidney failure, leukaemia, polycythmia, thalassemia, thrombosis or an allergy to vitamin C. It could also cause problems in people with sickle cell anaemia, G-6PD Deficiency, kidney stones or gout. Pregnant and breast-feeding woman consult a physician prior supplementation

Known Symptoms Of Over Dosage And Particulars Of Its Treatment:

For symptoms of overdosage please see “SIDE EFFECTS AND SPECIAL PRECAUTIONS
The treatment of overdosage is symptomatic and supportive.